Acomplia is the first drug in a new therapeutic agent category named Cannabinoid-1 Receptor Blockers, or simply CB-1. It is used for the treatment of obesity and associated issues.
How Does Acomplia Function?
Acomplia selectively blocks CB1 receptors located in the brain and peripheral parts of the body in fat and glucose metabolism, involving adipose tissue, muscle, gastrointestinal tract, and liver. The drug turns off the same brain cycles, which make people hungry during the smoking of marijuana. Acomplia CB1 receptor blocking decreases the super activity of endocannabinoid system. It is a physiological system, which involves such receptors, as the CB1, and has been displayed to have a significant role in the regulation of weight and energy balance control and the metabolism of fat and glucose.
The Use of Acomplia
Acomplia is an additional medicine taken during diet and exercise for the treatment of overweight and obese patients suffering from abnormal fat levels in their blood and from Type 2 diabetes. It is also believed that Acomplia may prevent the cardiovascular disease risk, although not proved. Most patients with large waist circuit will benefit from taking this medicine.
Does Acomplia Also Help to Stop Smoking?
Acomplia has been well-researched as a smoking cessation aid based on researches for about a year in more than 6,500 smokers, who wanted to quit the habit. However, it hasn’t proved to help smokers quit the habit and it didn’t get approved for this use. Acomplia is only approved to be used in weight control.
Acomplia Side Effects
According to the researches of Acomplia in obesity treatment, the medicine’s side effects were nausea and vomiting. In the trial, 19% of patients have left it due to these effects and 13% of patients have suffered the same side effects, although they were taking placebo.
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